German scientists witnessed a new development in the mini-brains they grew from stem cells in the laboratory, which the scientific community had never seen before. These mini-brains, which are grown in a special bacterial breeding dish called Petri, to develop primitive eye structures on their own succeeded.

For the first time in history, mini-brains that can send signals to the brain tissue, according to the statement made by scientists, will be developed in the future. eye diseases, development and differentiation processes of eyes will allow for better understanding and analysis.

Mini brains have neural networks containing lens and corneal tissue

These mini-brains, called brain organoids, are tissue that scientists have long grown in vitro for many different studies, such as monitoring drug reactions and cell development. Although their appearance resembles a human brain, brain organoids are far from being a real brain. These are collected from adult humans and thanks to reverse engineering of stem cells are 3 sizedollar water tissues that have the potential to transform into many different tissue types.

These orgaonids, which do not have any features such as thought, emotion and consciousness like the human brain, and can only imitate brain tissue bubbles, were discovered this time by scientists working at the University Hospital of Dusseldorf. to observe eye development was bred. Scientists have done many studies on brain organoids before,

However, for the first time in history, a brain organoid, to develop their own tick eye structures, albeit at a primitive degree. succeeded:

Scientists used two different cells to create mini-brains to monitor eye development. One of these cells from a stem cell that helps form the entire eyeball during embryo development consisted of. Carefully grown brain organoids, just as in human development It started to form optic spheres in a short time like 30 days and these structures were clearly visible at the end of the 50th day. This optic sphere formed by organoids, from neural networks that can respond to light and even include lens and corneal tissue consisted of.

Stating that such a thing has happened for the first time in the world of science, scientists said, Articles published in the scientific journal Cell Stem Cell expressed the following words; “Eye development is a complex process, and understanding this may allow understanding of the molecular basis in early retinal diseases. It is therefore crucial to study the optic vesicles, which we refer to as the primordium of the eye, which are essential for proper eye formation.”

Neuroscientist Jay Gopalakrishnan, one of the names at the beginning of the research, included the following statements; “Our work demonstrates the remarkable ability of brain organoids to generate primitive sensory structures that are light-sensitive and contain cell types similar to those found in the body. These organoids have been instrumental in studying brain-eye interactions during embryo development, modeling congenital retinal disorders, and for personalized drug testing and transplantation treatments. It can help create patient-specific retinal cell types.”

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Michael Lewis


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